Dendrimer-conjugated podophyllotoxin suppresses DENA-induced HCC progression by modulation of inflammatory and fibrogenic factors
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منابع مشابه
overexpression of annexin a1 suppresses pro-inflammatory factors in pc12 cells induced by 1-methyl-4-phenylpyridinium
objective: annexin a1 (anxa1) is suggested to have anti-inflammatory function. however, the precise function of anxa1 has remained unclear. in this study, we therefore examined the potency of anxa1 in regulating reactive oxygen species (ros) production and suppressing pro-inflammatory responses in pc12 cells induced by 1-methyl-4-phenylpyridinium (mpp+). materials and methods: in this experimen...
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Polyunsaturated fatty acids (PUFA) can modulate the immune response, however the mechanism by which they exert this effect remains unclear. Previous studies have clearly demonstrated that the cis-9, trans-11 isomer of conjugated linoleic acid (c9,t11-CLA), found predominantly in beef and dairy products, can modulate the response of immune cells to the toll-like receptor (TLR) 4 ligand, lipopoly...
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The thalamus is a central element for the generation of rhythmic oscillatory activity under physiological and pathophysiological conditions. Especially slow oscillations in the delta and theta frequency band which normally occur during slow-wave sleep are associated with a number of neuropsychiatric conditions if they occur during wakefulness and may be the basis for the generation of character...
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Kidney cancer is the third most common malignancy of the genitourinary system account for 2 to 3 % of all cancers in men worldwide, with 130,000 new cases and 63,000 deaths from the disease occurring annually (Ferlay et al., 2004). Certain toxic chemicals and medicines can cause renal damage, are recognized as a toxicological problem. NNitrosodiethylamine (DENA) is the most important environmen...
متن کاملAnti-Inflammatory Effects of Atorvastatin by the Modulation of NF-κB Expression during Hyperglycemia-Induced Nephropathy in Rat
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ژورنال
عنوان ژورنال: Toxicology Research
سال: 2019
ISSN: 2045-452X,2045-4538
DOI: 10.1039/c9tx00103d